Who Target Product Profiles : WHO Target Product Profiles for COVID-19 Vaccines.

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The WHO published a Target Product Profile (TPP) for NiV vaccines in 2017 [15]. The TPP lists 12 preferred characteristics for vaccine candidates, including target population, dose regimen, and durability of protection. In addition, the TPP lists the critical characteristics in case a candidate does not meet each of the preferred

This publication contains four Target Product Profiles (TPPS) for antibacterial treatments for enteric fever, gonorrhoea, neonatal sepsis and urinary tract infections, together with the report of the meeting of the scientific advisory group that developed the TPPs. These target product profiles are intended to highlight the diagnostic tools needed for the future strategies to combat human African trypanoso-miasis, and to facilitate the decision processes for potential product devel-opers and donors.

TARGET PRODUCT PROFILES FOR NEEDED ANTIBACTERIAL AGENTS: enteric fever, gonorrhoea, neonatal sepsis, urinary tract infections and meeting report

Key resources on developing target product profiles

Background The Target Product Profile (TPP) is a tool used in industry to guide development strategies by addressing user needs and fostering effective communication among stakeholders. However, they are not frequently used in academic research, where they may be equally useful. This systematic review aims to extract the features of accessible TPPs, to

01 TPP是什么？目标产品特征（Target Product Profile，TPP）是表明计划研发的试验药最理想特征的文件，是对新产品的预期安全性、有效性/有效性和价 Links to WHO target product profiles (TPPs) and product profile characteristics (PPCs) For a searchable database of WHO and non-WHO TPP and PPC addressing global health concerns, please visit the TPP Directory here. For a list of WHO TPP and PPC by disease area, please see below. Antimicrobial resistance WHO Target Product Profiles for mpox Vaccines Version 1, 16 August 2024 Purpose of the document Selected disease areas are identified as WHO priorities for research and product development. In the case of mpox1, target product profile development followed evidence of increasing transmission and possible need to make one or more vaccines

The WHO target product profiles for HPV screening tests aim to guide innovation and motivate test developers and manufacturers to create solutions that meet global health needs to help us reach the global target of 70% screening coverage with high-performance tests in communities everywhere. Overview This Target Product Profile (TPP) describes the preferred and minimally acceptable profiles for human vaccines for long term protection

Target Product Profile — A Strategic Development Process Tool DRAFT GUIDANCE This guidance document is being distributed for comment purposes only. Comments and suggestions regarding this draft document should be submitted within 60 days of publication in the Federal Register of the notice announcing the availability of the draft guidance. As a prerequisite to building a portfolio strategy, the desired R&D outcome for each disease is defined as the target product profile (TPP). Each R&D project in the portfolio is selected, progressed, and managed according to well-defined decision matrices based on these TPPs.

April 2023 TARGET PRODUCT PROFILE PLAYBOOK
Target product profiles for tests used for
Frequently Asked Questions
WHO Target Product Profiles for mpox Vaccines

The Target Product Profile Directory (TPPD) is a free-to-use online resource to improve the efficiency of efforts to develop new products for neglected diseases and populations as well as threats to global health. It is a searchable database of desired health products and their key characteristics. The database includes product profiles for medicines, vaccines, diagnostics The target audience for the target product profiles is broad and includes clinicians, researchers working on diagnostics, laboratory experts, including, microbiologists and virologists, public health experts, epidemiologists, developers, and representatives for manufactures, including biotech engineers, policy-and decision-makers as well as The importance of target product profiles resides in their role in identifying the critical attributes of a product before development begins, to ensure that the final product is adapted and responds to the needs of the end-users (Fig. 7.1). Target product profiles can help address issues early in the product development process and prevent late-stage development failures.

WHO Target Product Profiles for COVID-19 Vaccines.

Purpose of the document Selected disease areas are identified as WHO priorities for research and product development. In the case of COVID-19, target product profile development followed the COVID-19 Global research and innovation forum: towards a research roadmap1. This target product profile2 is intended to convey, based on the most recently available data, WHO’s In 2014, the World Health Organization (WHO) published target product profiles (TPPs) which detailed minimal and optimal criteria to address high-priority TB diagnostic needs. Since then, the TB community’s needs have evolved; there has been a surge

Key resources CREATE bio example: target product profile (TPP) National Institute of Neurological Disorders and Stroke What’s the regulatory value of a target product profile? Trends Biotechnol 2017 Note for guidance on pharmaceutical development European Medicines Agency, 2009 Vaccine development process map UK Medical Research Council A Target Product Profile (TPP) is a strategic planning tool that guides the development of safe and effective medical products. It outlines the desired product characteristics, including its intended use, target population, and key performance features, ensuring that efforts in research and development align with specific clinical needs and regulatory requirements. By

TPP: For COVID-19 Vaccines
Revised version, April 2022
Target Product Profiles and Target Candidate Profiles
Bulletin of the World Health Organization
Target Product Profiles for Medical Product Development

To inform the research and development targets for funders and developers, the World Health Organization (WHO) has developed new target product profiles (TPPs) for tests for TB treatment monitoring and optimization.

Target product profiles (TPPs) or preferred product characteristics (PPCs) documents are planning tools for the development of health products. TPPs and PPCs specify the intended use, target populations and desired attributes of products and guide research and development (R&D) outputs for funders and developers. Contributors These TPPs were developed according to a process based on the WHO document: Target Product Profiles, Preferred Product Characteristics, and Target Regimen Profiles: Standard Procedure, version 1.03 dated 7 December 2021. The World Health Organization (WHO) has published today updated Target Product Profiles (TPPs) for tuberculosis diagnosis and detection of drug resistance. These TPPs define the most important characteristics and requirements to be considered in the development of new TB diagnostics.The document consolidates two TPPs for TB diagnostics to be carried

The TPP development group consisted of scientific, clinical, and public health experts from diverse geographic regions and was established to develop a target product profile for the 6 selected priority formulations and to provide clear guidance for manufacturers and product development partnerships.

Target Product Profile of mRNA Dengue Vaccine * Case definition: A virologically-confirmed dengue case is defined as febrile illness (defined as temperature ≥38°C on any 2 of 3 consecutive days) or illness clinically suspected to be dengue by the Investigator with a positive serotype-specific RT-PCR. EXECUTIVE SUMMARY Target Product Profile (TPP) is a strategic document that summarizes the features of an innovation needed to address an unmet need. While TPPs are a valuable way to address market shortcomings, they currently remain underutilized. This TPP playbook serves as a resource guide on how to design and conduct a formalized, step-wise, consensus based Health ministries currently lack effective tools for monitoring and evaluation of schistosomiasis control programmes. Egg detection can be used, but the cost, challenges of obtaining samples, and the need for trained personnel

WHO Target Product Profiles for mpox Vaccines

WHO Target Product Profiles for mpox Vaccines Version 1, 16 August 2024 Purpose of the document Selected disease areas are identified as WHO priorities for research and product development. In the case of mpox1, target product profile development followed evidence of increasing transmission and possible need to make one or more vaccines TPP: For COVID-19 Vaccines WHO Target Product Profiles for COVID-19 Vaccines Revised version, April 2022 1 April 2022 II. Target Product Profiles Roadmap strategic goal: Develop and make vaccines available under Emergency Use Authorization Listing or Licensure that will protect people around the world from adverse health consequences caused by COVID-19, particularly hospitalization and death.

The team at Boyds are strong advocates of using Target Product Profiles to help clarify what needs to be achieved when developing products

A Target Product Profile (TPP) is a framework for the development of therapeutic candidates that summarises key features of an intended commercial product. A well-designed TPP provides a clearly articulated set of goals that help focus and guide development activities to reach the desired commercial outcome. In response, to increase access to quality-assured, accurate and affordable mpox (monkeypox) diagnosis, an expert consultation process has been initiated, resulting in the drafting of two target product profiles (TPPs): 1. Tests used for diagnosis within health care settings and laboratories (TPP1). 2.

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