Risk Factors For Insidious Uveitis In The Knabstrupper Breed
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Explore the Knabstrupper Horse breed. Learn about this spotted Danish warmblood breed history, characteristics, and uses for various equestrian disciplines.
Risk factors for insidious uveitis in the Knabstrupper breed Article Oct 2022 EQUINE VET J Nicole B. Kingsley Lynne Sandmeyer Sarah E. Parker Ann Dwyer Rebecca R. Bellone

Lynne S. Sandmeyer’s 21 research works with 113 citations and 616 reads, including: Risk factors for insidious uveitis in the Knabstrupper breed Risk factors for insidious uveitis in the Knabstrupper breed Equine Veterinary Journal 2023-09 | Journal article DOI: 10.1111/evj.13879
Lynne S. Sandmeyer’s research works
References Evaluation of breed as a risk factor for sarcoid and uveitis in horses , the potential cause of congenital stationary night blindness and coat spotting patterns (LP) in the Appaloosa horse ( : a candidate gene for leopard complex (LP) spotting and congenital stationary night blindness in horses
Explore the Knabstrupper Horse breed. Learn about this spotted Danish warmblood breed history, characteristics, and uses for various Previous investigations, however, have consistently identified age and homozygosity for the breed-defining coat patterning allele (LP, for leopard complex spotting pattern) as risk factors for Equine recurrent uveitis (ERU) is the leading cause of blindness for horses; previous research implicated the leopard complex spotting allele (LP) as a genetic risk factor for insidious uveitis in the Appaloosa.
Previous investigations, however, have consistently identified age and homozygosity for the breed-defining coat patterning allele (LP, for leopard complex spotting pattern) as risk factors for
- Risk Factors for Equine Recurrent Uveitis
- Medical and Surgical Management of Equine Recurrent Uveitis
- Sarah Parker’s research works
- Equine Genetic Projects of Dr. Rebecca Bellone
文献「Knabstrupper品種における伝染性ぶどう膜炎の危険因子【JST・京大機械翻訳】」の詳細情報です。J-GLOBAL 科学技術総合リンクセンターは研究者、文献、特許などの情報をつなぐことで、異分野の知や意外な発見などを支援する新しいサービスです。またJST内外の良質なコンテンツへ案内いたし Risk factors for insidious uveitis in the Knabstrupper breed. Kingsley NB, Sandmeyer L, Parker SE, Dwyer A, Heden S, Reilly C, Hallendar-Edman A, Archer S, Bellone RR Equine Vet J, 55 (5):820-830, 24 Oct 2022 Cited by: 0 articles | PMID: 36199161 Genetic risk factors for insidious equine recurrent uveitis in Appaloosa horses. Abstract: Appaloosa horses are predisposed to equine recurrent uveitis (ERU), an immune-mediated disease characterized by recurring inflammation of the uveal tract in the eye, which is the leading cause of blindness in horses.
Knabstrupper Horse Breed Guide: Characteristics, Health
Request PDF | Medical and Surgical Management of Equine Recurrent Uveitis | Equine recurrent uveitis (ERU) is characterized by recurrent bouts of inflammation interrupted by periods of quiescence Risk factors for insidious uveitis in the Knabstrupper breed. Equine Vet J. 2023 Sep; 55 (5):820-830. Kingsley NB, Sandmeyer L, Parker SE, Dwyer A, Heden S, Reilly C, Hallendar-Edman A, Archer S, Bellone RR. PMID: 36199161.

Risk factors for insidious uveitis in the Knabstrupper breed Article Oct 2022 Nicole B. Kingsley Lynne Sandmeyer Sarah E. Parker [] Rebecca Bellone Risk factors for insidious uveitis in the Knabstrupper breed Kingsley, Nicole B.; Sandmeyer, Lynne; Parker, Sarah E. et al. Risk factors for insidious uveitis in the Knabstrupper breed Article Oct 2022 Nicole B. Kingsley Lynne Sandmeyer Sarah E. Parker [] Rebecca Bellone
However, the causative variant in the region containing LP is suspected to have incomplete penetrance for ERU, and identification of other breed-specific risk factors, such as the associated region on ECA X, will help to better explain the distribution of insidious uveitis within the Appaloosa, Knabstrupper, and POA breeds.
Citations (1) References (163) Risk factors for insidious uveitis in the Knabstrupper breed Article Oct 2022 Nicole B. Kingsley Lynne S. Sandmeyer Sarah Parker Rebecca Bellone References Evaluation of breed as a risk factor for sarcoid and uveitis in horses , the potential cause of congenital stationary night blindness and coat spotting patterns (LP) in the Appaloosa horse ( : a candidate gene for leopard complex (LP) spotting and congenital stationary night blindness in horses
Because horses with insidious uveitis are often presented when irreversible disturbances of vision, which cannot be removed by a CsA-implant, have already occurred, a routine eye examination of the hor-ses of the endangered breeds (Appaloosa horses, Knabstruppers) and leopards is recommended. However, the causative variant in the region containing LP is suspected to have incomplete penetrance for ERU, and identification of other breed-specific risk factors, such as the associated region on ECA X, will help to better explain the distribution of insidious uveitis within the Appaloosa, Knabstrupper, and POA breeds.
VGL Research: An international collaboration identified that homozygosity for leopard complex spotting allele (LP) is a risk factor for insidious uveitis in the Knabstrupper horse. However, the causative variant in the region containing LP is suspected to have incomplete penetrance for ERU, and identification of other breed-specific risk factors, such as the associated region on ECA X, will help to better explain the distribution of insidious uveitis within the Appaloosa, Knabstrupper, and POA breeds. Request PDF | Genetic risk factors for insidious equine recurrent uveitis in Appaloosa horses | Appaloosa horses are predisposed to equine recurrent uveitis (ERU), an immune-mediated disease
Risk Factors for Equine Recurrent Uveitis
Previous investigations, however, have consistently identified age and homozygosity for the breed-defining coat patterning allele (LP, for leopard complex spotting pattern) as risk factors for
VGL Research: An international collaboration identified that homozygosity for leopard complex spotting allele (LP) is a risk factor for insidious uveitis in the Knabstrupper horse. The study led by
Risk factors for insidious uveitis in the Knabstrupper breed Article Oct 2022 Nicole B. Kingsley Lynne Sandmeyer Sarah E. Parker [] Rebecca Bellone VGL Research: An international collaboration identified that homozygosity for leopard complex spotting allele (LP) is a risk factor for insidious uveitis in the Knabstrupper horse.
Leider ist die sogenannte schleichende Uveitis (engl. insidious uveitis, „Tigerscheckenuveitis“), die vor allem Tigerschecken, Isländer und Kaltblüter betrifft und oft bilateral auftritt, besonders schwer zu diagnostizieren. Risk factors for insidious uveitis in the Knabstrupper breed Kingsley, Nicole B.; Sandmeyer, Lynne; Parker, Sarah E. et al. The study led by VGL director, Dr. Rebecca Bellone, examined 116 Knabstrupper horses from Denmark, Sweden and the Unites States, and determined that uveitis in the Knabstrupper is quite similar to that of the Appaloosa, supporting the use of genotyping for LP to assess risk and help inform clinical management decisions for equine recurrent uveitis in this breed.
Objective: To characterize clinical manifestations, measure frequency, and evaluate risk factors for equine recurrent uveitis (ERU) in Appaloosa horses in western Canada. Animals: 145 Appaloosa
This study suggests that insidious uveitis is highly heritable (REML 95% CI, h2 = 0.68–1.0) and additional loci outside of LP are contributing to the genetic risk for insidious uveitis for
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