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Disparities In Early-Onset Colorectal Cancer

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Steep increases for early onset colorectal cancer, from 18.8 cases per 100,000 Native Alaskans aged 20–49 years during 1998 through 2002 to 34.8 cases per 100,000 during 2014 through 2018, exacerbated this disparity. Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality in the US,1 with persistent disparities by race and ethnicity.2 Non-Hispanic Black individuals have some of the highest rates of CRC incidence and mortality. Background: Survival is reduced in African–Americans (AAs) diagnosed with colorectal cancer (CRC), especially in those <50 years old, when compared with Caucasian Americans (CAs). Yet, the role of

Early-onset cancers: Biological bases and clinical implications

Effective patient-centered communication tailored to the specific needs of racial and ethnic minorities through primary care initiatives may have potential for improving early detection and outcomes, particularly for younger populations and racial minorities. Background The burden of early onset colorectal cancer (EOCRC) falls disproportionately on minorities and individuals in specific geographic regions. While these disparities are likely multi-factorial, access to high-quality health care plays a significant role. We sought to determine if Medicaid expansion is associated with reducing racial disparities in FOR MORE INFORMATION, CONTACT: American Cancer Society, [email protected] Abstract #6544 ATLANTA, May 26, 2022 — In a new large national study led by researchers at the American Cancer Society (ACS), Black patients diagnosed with early-onset colorectal cancer received worse and less timely care than their white

Geographic and intra‐racial disparities in early‐onset colorectal ...

Background: The mortality rates of early-onset colorectal cancer (EOCRC) have surged globally over the past two decades. While the underlying reasons remain largely unknown, understanding its epidemiology is crucial to address this escalating trend. This study aimed to identify disparities potentially influencing these rates, enhancing risk assessment tools, and Early onset colorectal cancer (EOCRC), defined as colorectal cancer diagnosed before 50 years of age is on the rise. We have seen an alarming increase in incidence of EOCRC around the world over the past two decades. A recent systematic review published in BMC Cancer that included 40 studies from 12 countries across five continents showed a worldwide

Abstract Background: Although early-onset colorectal cancer (EOCRC) incidence rates (IRs) are increasing, geographic and intra-racial IR disparities are not well defined. There are significant racial and ethnic disparities in the incidence and outcomes of early onset Colorectal Cancer (eoCRC) There is a notable gap in research regarding the stratification of Hispanic patients by country-of-origin. The aim is to analyze demographic, clinical, and oncologic outcomes among Hispanic-American sub-populations. ATLANTA, November 8, 2023 — In a new, large national hospital-based study, researchers at the American Cancer Society (ACS), found individuals racialized as Black in the United States with early-onset colorectal cancer received worse and less timely, guideline-concordant care than individuals racialized as White. This cancer care included surgery, chemotherapy, and

Since the nineties, the incidence of sporadic early-onset (EO) cancers has been rising worldwide. The underlying reasons are still unknown. However, identifying them is vital for advancing both prevention and intervention. Here, we exploit available knowledge derived from clinical observations to formulate testable hypotheses aimed at defining the causal factors of Colorectal cancer (CRC) is one of the four most common cancers and the third leading cause of cancer-related deaths in Guam. This study investigated CRC incidence, screening, and risk factors of early onset CRC across Guam’s ethnic groups using data from the Guam Cancer Registry (1998–2020) and the Guam Behavioral Risk Factor Surveillance Early onset colorectal cancer (EOCRC) emerged as the fourth foremost contributor to cancer-related mortality among both genders in the late 1990s. Presently, EOCRC (<50) ranks as the leading cause of cancer mortality in men and the second leading cause in women within the United States.

Elevated early-onset CRC rates were observed for both CHamorus and the broader Guam population under 50. The findings support the new recommendation to begin screening at age 45 and efforts to increase screening in Guam. Background Young adults diagnosed with colorectal cancer (CRC) comprise a growing, yet understudied, patient population. We estimated 5-year relative survival of early-onset CRC and examined disparities in survival by race-ethnicity in a population-based sample.

  • Disparities in Early Onset Colorectal Cancer
  • Racial and Ethnic Variation in Survival in Early-Onset Colorectal Cancer
  • Early-Onset Colorectal Cancer: Current Insights

26Background: Research is needed to understand the extent to which the incidence of early onset colorectal cancer (EOCRC)is rising across population sub-groups, including by age, sex, race/ethnicity, and urbanicity, to inform hypotheses regarding its Editorial: Disparities in early onset colorectal cancerFront Oncol. 2024 Dec 19:14:1537473. doi: 10.3389/fonc.2024.1537473. eCollection 2024.

Abstract Background Incidence rates (IRs) of early-onset colorectal cancer (EOCRC) are increasing, whereas average-onset colorectal cancer (AOCRC) rates are decreasing. However, rural-urban and racial/ethnic differences in trends by

Multiethnic Trends in Early Onset Colorectal Cancer

Abstract e15700 Background: The incidence of early-onset colon cancer (EO-CC) is rising, but it remains unclear whether EO-CC represents a biologically distinct entity compared to colon cancer in patients aged > 50g. This study analyzed early-onset CC demographics, clinical features, and outcomes using the National Cancer Database

Abstract Introduction: Early-onset colorectal cancer (EO-CRC) is a public health concern. Starting screening at 45 years has been considered, but there is discrepancy in the recommendations. Racial disparities in EO-CRC incidence and survival are reported; however, racial/ethnic differences in EO-CRC features that could inform a racial/ethnic-tailored CRC

Keywords: colorectal cancer, disparities, early‐onset colorectal cancer, Hispanic, racial and ethnic 1. Introduction Nearly 1.9 million colorectal cancer (CRC) cases are diagnosed each year globally [1, 2]. Although CRC is potentially preventable, it continues to be the second most diagnosed cancer in the United States and Puerto Rico [3]. In the last decade, overall rates of colorectal cancer have been falling among the general population in the US. However, African Americans are more likely to develop colorectal cancer at younger ages, and to die from it. The reasons for this disparity are unclear, but they are rooted in socioeconomic

Request PDF | Racial/Ethnic Disparities in Early-Onset Colorectal Cancer Outcomes | Although some researchers have examined EO-CRC clinical presentations, much of this research has focused on non Specifically, early-onset patients lacked BRAF mutations, whereas almost 40% of late-onset patients had BRAF mutations. 3 BRAF mutations were further examined by Perea and colleagues who defined early-onset colorectal as cancer found in individuals younger than 45 years and studied a total of 88 patients. Conclusion Persistent racial/ethnic disparities in patients with colorectal cancer, especially in AI/AN and Black, call for new interventions to eliminate health disparities. Our study provides vital evidence to address racial/ethnic inequality.

Advancing early onset colorectal cancer research: research advocacy, health disparities, and scientific imperatives

Steep increases for early onset colorectal cancer, from 18.8 cases per 100,000 Native Alaskans aged 20-49 years during 1998 through 2002 to 34.8 cases per 100,000 during 2014 through 2018, exacerbated this disparity.

Native Hawaiian and non-Hispanic Black individuals had the highest burden of mortality among patients with early-onset colorectal cancer (CRC). Colorectal cancer (CRC) is the third most common cancer worldwide and the fourth leading cause of cancer death in the world.1 As in other tumours, there are differences in incidence according to sex. The mortality rates of early-onset colorectal cancer (EOCRC) have surged globally over the past two decades. While the underlying reasons remain largely unknown, understanding its epidemiology is crucial to address this escalating trend. This study

Abstract Background Incidence rates (IRs) of early-onset colorectal cancer (EOCRC) are increasing, whereas average-onset colorectal cancer (AOCRC) rates are decreasing. However, rural-urban and racial/ethnic differences in trends by

Abstract Purpose: Young individuals racialized as Black are more likely to die after a colorectal cancer (CRC) diagnosis than individuals racialized as White in the United States. This study examined racial disparities in receipt of timely and guideline-concordant care among individuals racialized as Black and White with early-onset CRC. A study of early-onset colorectal cancer found significant racial disparities, with younger patients more frequently diagnosed at advanced stages. Young individuals racialized as Black are more likely to die after a colorectal cancer (CRC) diagnosis than individuals racialized as White in the

Abstract Early-onset colorectal cancer (EOCRC) has seen an alarming rise worldwide over the past two decades. The reason for this global trend is poorly understood. EOCRC appears to have its own unique clinical and molecular features when compared with late-onset colorectal cancer. Younger patients appear to have more distal or rectal disease, a more advanced stage of