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5 Top Emerging Startups Tackling Neurodegenerative Diseases

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Top Neurodegenerative Diseases Drugs startups There are 736 Neurodegenerative Diseases Drugs startups which include Denali Therapeutics, Intra-Cellular Therapies, Amylyx Pharmaceuticals, Annexon, Alector. Out of these, 461 startup s are funded, with 239 having secured Series A+ funding. Since the G8 dementia summit in 2013, a number of initiatives have been established with the aim of facilitating the discovery of a disease-modifying treatment for dementia by 2025. This report is a summary of the findings and recommendations of a meeting titled “Tackling gaps in developing life-changing treatments for dementia”, hosted by Alzheimer’s

Neurodegenerative diseases (NDs), including Alzheimer’s disease (AD) and Parkinson’s disease (PD), are among the most prevalent neurological disorders affecting middle-aged and older individuals. These diseases are characterized by progressive neuronal loss and dysfunction that lead to severe impairments in cognition and movement. Current research Startups in the field of Alzheimer’s disease treatment are developing innovative technologies such as precision medicine, gene therapies, immunotherapies, and neurostimulation techniques to target the underlying causes and symptoms of the disease.

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Biochemical and Molecular Pathways in Neurodegenerative Diseases: An ...

Yumanity is working to identify and develop new, disease-modifying therapies that address several illnesses with critical unmet medical needs. The initial focus of the company is neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis (ALS). Country: Israel | Funding: $63.1M BrainStorm Cell Therapeutics is a biotechnology company developing innovative, autologous stem cell therapies for highly debilitating neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS, also known as Lou Gehrig’s disease), Multiple Sclerosis (MS) and Parkinson’s Disease (PD). Discover the top emerging companies in the Rare Neurology Diseases Drugs Startups, their funding activity, key investors, company highlights, and growth stages

Alector Funding: $269.5M Alector is a hypothesis-driven, neurology-focused startup that’s pioneering the discovery and development of first-in-class, immuno-modulatory therapies for Alzheimer’s disease and other neurodegenerative disorders.

Neurodegenerative diseases pose significant challenges to healthcare systems globally due to their complex etiology and relentless progression, often rendering conventional treatments ineffective. Recent advances have spotlighted excitatory amino acids, particularly D-amino acids, once considered as Learn about the causes, symptoms, and progression of neurodegenerative diseases, with a focus on treatment to slow the decline and improve quality of life. June 18, 2025 French HealthTech company DESKi raises €5.2 million for its cardiac imaging software March 6, 2025 TRIMTECH Therapeutics raises

Cardiology startups develop new heart diagnostics, treatment and regeneration technologies, like genome analysis, AI-powered diagnostics, stem cells, ECG apps and gadgets, new drugs, implantable pulse generators, heart

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Top start-ups for neurodegenerative diseases at VentureRadar with Innovation Scores, Core Health Signals and more. Including HDAX Therapeutics, Coya Therapeutics etc

Neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and Multiple Sclerosis present a formidable challenge in medicine due to their progressive nature and the brain’s complex architecture. Current treatments, while providing some relief, often fall short of halting or reversing disease progression. This is where the emerging field of medical nanobots comes into focus. Alpha Cognition is a clinical stage, biopharmaceutical company developing treatments for neurodegenerative diseases such as Alzheimer’s Dementia and Amyotrophic Lateral Sclerosis (ALS).

Explore neurodegenerative disorder gene therapy companies like Prevail Therapeutics and AviadoBio, developing innovative treatments for critical diseases. Aging is a major risk factor for neurodegenerative diseases and, as lifespans are increasing, these health challenges are becoming more prevalent. An age-associated loss in neural stem cell number and/or activity could cause this decline in brain function, so interventions that reverse aging in stem cells might increase the human cognitive Gene therapy is rapidly emerging as a powerful therapeutic strategy for a wide range of neurodegenerative disorders, including Alzheimer’s disease (AD), Parkinson’s disease (PD) and Huntington’s disease (HD). Some early clinical trials have failed to achieve satisfactory therapeutic effects. Efforts to enhance effectiveness are now concentrating on three major

AviadoBio is a pioneer in gene therapy, aiming to research how genes can help combat neurodegenerative diseases like dementia. Their research focuses on developing therapies and treatments that can slow or even halt the progression of

Heat Map: 5 Top Antibiotic Resistance Startups Using our StartUs Insights Platform, covering 1.116.000+ startups & emerging companies, we looked at innovation in the field of pharma. For this research, we identified 96 relevant solutions and picked 5 to showcase below. These companies were chosen based on a data-driven startup scouting approach, taking into account This review highlights the key physiological functions of the TDP-43 protein, while considering an expanding spectrum of neurodegenerative diseases associated with pathogenic TDP-43 deposition, and dissecting key molecular pathways through which TDP-43 may mediate neurodegeneration. Keywords: ALS; motor neuron disease; motor physiology.

5 Top Emerging Biopharmaceutical Startups

In this article, we will explore the top 10 small to medium size biotech companies working in the field of neurodegenerative diseases and highlight their product portfolios, current clinical

Discover 5 global startups & scaleups in this data-driven report & learn how their food security solutions impact your community!

NRG Therapeutics Back to Top NRG Therapeutics describes itself as a neuroscience-focused drug discovery company building a pipeline of disease-modifying drug candidates, using therapeutic approaches to restore mitochondrial function while slowing or halting the progression of neurodegenerative diseases, such as Parkinson’s and ALS. Heat Map: 5 Top Emerging Startups Tackling Fake News Using our StartUs Insights Discovery Platform, covering 1.379.000+ startups & scaleups globally, we looked at innovation in the field of news & media. For this research, we identified 331 relevant solutions and picked 5 to showcase below. These companies were chosen based on a data-driven startup scouting approach,

Heat Map: 5 Top Startups Tackling Neglected Tropical Diseases Using our StartUs Insights Platform, covering 1.116.000+ startups & emerging Year founded: 2020 Location: Seattle, Washington Funding: $96M (Series A) What they do: Cajal Neuroscience is a Seattle-based biotechnology company that develops new drugs for neurodegenerative diseases. Specifically, the startup integrates human genetics, functional genomics, and advanced microscopy to identify novel targets for These leading neuroscience startups are pioneering breakthroughs poised to fundamentally transform the approach to brain health

We analyzed 575 biopharmaceutical startups. NeuroScientific Biopharmaceuticals, CellmAbs, Rheos Medicines, Avicanna & AptaTargets develop 5 top solutions! Out of 139, the Global Startup Heat Map highlights 5 Top Startups Tackling Malaria Startups such as the examples highlighted in this report focus on malaria hotspot identification, microscopy-based diagnostics, phage-based malaria detection, and infectious disease therapeutics. While all of these technologies play a significant role in advancing healthcare, they only represent the tip With the population getting older and with a corresponding increase in neurodegenerative diseases (NDs) worldwide, developing drug delivery systems that can overcome conventional barriers in treating these diseases is the need of the hour. Drug delivery by nanotechnology has great promise for detecting and treating a wide range of

Neuroinflammation refers to a highly complicated reaction of the central nervous system (CNS) to certain stimuli such as trauma, infection, and neurodegenerative diseases. This is a cellular immune response whereby glial cells are activated, inflammatory mediators are liberated and reactive oxygen a Alector is a hypothesis-driven, neurology-focused startup that’s pioneering the discovery and development of first-in-class, immuno-modulatory therapies for Alzheimer’s disease and other neurodegenerative disorders. Detailed info and reviews on 5 top Neurology companies and startups in France in 2025. Get the latest updates on their products, jobs, funding, investors, founders and more.

TDP-43 proteinopathies: a new wave of neurodegenerative diseases

However, the current symptomatic and disease-modifying therapies have achieved limited benefits for neurodegenerative diseases in clinical settings.

Moreover, we benchmark emerging technologies that have been adopted by top pharmaceutical companies looking to bridge the gap between drug discovery and drug development in neurodegenerative disease.